OPENCOMET: AN AUTOMATED TOOL FOR COMET ASSAY IMAGE ANALYSIS

OpenComet: An automated tool for comet assay image analysis

Reactive species such as free radicals are constantly generated in vivo and DNA is the most important target of oxidative stress.Oxidative DNA damage is used as a predictive biomarker to monitor the risk of development of many diseases.The comet assay is widely used for measuring oxidative DNA damage at a single cell level.The analysis of comet ass

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Immunotherapy and Asthma in Children

Allergen immunotherapy (AIT) is still the only disease-modifying treatment strategy for IgE-mediated allergic diseases, with consolidated evidence both in adults and children.AIT is effective in determining clinical improvement of allergic rhinitis and asthma, NANO VAPOR such as reduced symptoms, medication use, and improvement of quality of life,

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Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progressionResearch in context

Background: Triple-negative breast cancer (TNBC) remains difficult to be targeted.SET and cancerous inhibitor of protein phosphatase 2A (CIP2A) are intrinsic protein-interacting inhibitors of protein phosphatase 2A (PP2A) and frequently overexpressed in cancers, whereas reactivating PP2A activity has been postulated as an anti-cancer strategy.Here

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